Grinding Synthesis detailed procedure and scheme of the apparatus any changes to the original procedure, actual masses, and bobs yield calculations and pm Discussion outline Grained RSN (what is it used for, why important, the mechanism) Reaction set up (important details) How can the RSN be activated Second step: RSN of the Grained reagent with acetaminophen, quenching with ammonium chloride Isolation Of the product, identification Possible or actual sources of error Part one of our experiment consisted of the preparation of phenylalanine’s bromide from brokenness.
Pamper is an ergonomically reagent, a class f nucleoli known as a Grained reagent. Grinding reagents are a class of extremely reactive chemical compounds used in the synthesis of hydrocarbons, alcohols, carboxylic acids, and other compounds. A grinding reagent is an organic magnesium halide dissolved in a nonrestrictive solvent (like ethyl ether).
The substance is made up of an organic group joined by a high polar covalent bond to magnesium, while magnesium is joined by an ionic bond to a halogen (like bromide) a grinding reagent will react with water, oxygen or almost any other electroscopic organic compound to produce alcohols, which makes it important in laboratories. Ergonomically reagents are strong bases that readily abstract a proton from H2O to form hydrocarbons because H2O is a stronger acid than the alkaline product of the acid-base reaction.
Similar reactions occur with the O-H proton in alcohols and carboxylic acids. Because of this, at the very beginning of our experiment, moisture was removed as it would react with our highly basic Grinding Reagents and destroy it. Thus a drying tube is necessary to remove any water that may be contained in our system. NO was also blown through the apparatus to clear all of the atmospheric gases (including H2O) from the apparatus.
In the formation of a Grained reagent (Arms) chemists sometimes use a chemical additive to activate the metal MGM surface in order for MGM to more readily react with the ORG group. Activators react with magnesium in those places where the magnesium oxide film has a small thickness or defective, the mechanical action improves activation. As a result, these places form cavities filled with a magnesium halide (like Mega or Mugger).
In our experiment, the addition of tiny crystals of Iodine to the reaction mixture were helpful in the removal of some of the MGM protecting the surface of TTL MGM strips, allowing the reaction to take place faster. In the second part of our experiment, the reaction of our Grinding reagent and acetaminophen resulted in our desired product of 1-1, departmentally, However the addition of ammonium chloride, a weak acid, was to facilitate the preparation of oxygen to produce an alcohol (DRAW MECHANISM) and bind to Mega into a water-soluble chloride.
Also, the weak acid is especially important as it helps us to avoid possible dehydration side RSN that can be triggered by strong acids (like HUH). The solution, after the addition of ammonium chloride, appeared to be a thin white suspension beneath a clue liquid. We isolated our product (after the addition ammonium chloride) by placing the resulting mixture and washing it consecutively with mm’ portions of watt ethyl ether, and brine, each time removing the resulting bottom aqueous layer.
Finally we added anhydrous magnesium sulfate to remove any reside aqueous portions, filtered, and readopted for 30 minutes until our solution evaporated all of the ether out. We followed by dissolving the product in proxy. 6 ml of methanol (to propionate any carnations left after the reactive took place), until it became cloudy (even after vigorous stirring) then finally lacing it in an ice bath to allow crystals to form. It took proxy. 30 minutes for crystals to form and required “scratching’ of the side of the flask to stimulate the crystals to form.
Also, to get the solution to crystallize, we add a few drops of water. After this step we quickly saw crystals appear after a few more minutes in the ice bath. After we got crystals, we collected them suction filtration and retrieved a total of 0. Egg. These crystals were white in color To identify that it was the correct product we found the melting point which was between 73 degrees Celsius to 80 degrees Celsius. That allowed to verify that we did indeed have 1 , 1 -departmentally.